Green Journals

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Novel 4-Anilinopyrimidine-N-Acylhydrazone derivatives as dual EGFRWT/VEGFR-2 tyrosine kinase inhibitors against non-small cell lung Cancer: Design, synthesis, biological evaluation, and computational studies

Tamer H. Ibrahim, Hanan H. Kadry, Khaled O. Mohamed et al.

2026-12 Vol. 185 Pages 110719

DOI: 10.1016/j.bioorg.2026.110719

Novel antioxidant peptides from silk sericin: virtual screening, molecular simulation and antioxidant mechanism

Wumei Chen, Xiaolan Xiao, Wenquan Ruan

2026-12 Vol. 185 Pages 110691

DOI: 10.1016/j.bioorg.2026.110691

Torijaponanes A–N, structurally diverse sesquiterpenoids from Torilis japonica with anti-inflammatory activity via suppression of NF-κB and MAPK activation

Zhao-Chun Zhan, Zhi-Shen Shao, Mei-Ting Weng et al.

2026-12 Vol. 185 Pages 110711

DOI: 10.1016/j.bioorg.2026.110711

Competitive inhibition of human carbonyl reductase 1 by the ketal-masked panaxfuraynes A and B: A computational–enzymatic study

Sang-Seop Lee, Sang Myung Lee, Jong Seok Kim et al.

2026-12 Vol. 185 Pages 110720

DOI: 10.1016/j.bioorg.2026.110720

Identification and characterization of a dual antagonist for mu and kappa opioid receptors from Menispermum dauricum DC

Jiaqi Huo, Fangfang Xu, Jixia Wang et al.

2026-12 Vol. 185 Pages 110721

DOI: 10.1016/j.bioorg.2026.110721

Bioactive molecules derived from cinnamon bark ameliorates depressive-like behavior through underlying neuroprotective mechanisms

Ying Zhao, Ya-Nan Fei, Hong-Lei Gao et al.

2026-12 Vol. 185 Pages 110746

DOI: 10.1016/j.bioorg.2026.110746

Facile synthesis, antibacterial activity, in silico molecular docking analysis, and pharmacokinetic properties of N-methyl anthranilate–based compounds

Fatma Salaheldin Mohamed, Mamdouh A. Abu-Zaied, Daniel Jan Strub et al.

2026-12 Vol. 185 Pages 110693

DOI: 10.1016/j.bioorg.2026.110693

A sequentially verified dual-lock near-infrared fluorescent probe for imaging lysosomal H2O2/microviscosity dynamics during radiotherapy and STING agonist sensitization

Xiaomin Huang, Yitong Liu, Yongfei Huang et al.

2026-12 Vol. 185 Pages 110736

DOI: 10.1016/j.bioorg.2026.110736

Isoeugenol-derived polyphenolic compounds modulate FOLFOX response, drug resistance, migration, and stemness-associated signatures in HT29 colon cancer cells and an HT29-CSC-enriched population

Sema Bilgin, Yahya Tayhan, Şeyma Yaşar et al.

2026-12 Vol. 185 Pages 110714

DOI: 10.1016/j.bioorg.2026.110714

Design, synthesis, and evaluation of anti-orthoflavivirus Anchimerically HINT1 Activatable (AHA) ProTides

Jigar Sethiya, Pratip Kumar Dutta, Bryan Magana et al.

2026-12 Vol. 185 Pages 110700

DOI: 10.1016/j.bioorg.2026.110700

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